On November 11, 2021, Matthias Kettwig, Gogentine University Medical Center, Germany, and his team , published a paper titled "Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy" on Nature Communications, which suggested that RNaseT2-/- mice can be used to study central nervous system damage associated with RnaseT2 defects.