精磊Apoptosis
学术研究
~~~高浓度EGFP抗体~~~NQBB血清+生长因子--效果奇佳~~~USCN ELISA Kit~~~Creative Biolabs抗体~~~治疗用抗体~~~核酸萃取仪~~~各式仪器~~~Bilfil各式耗材~~~

Apoptosis

相关连结 Click here











Apoptosis, or programmed cell death, characterized by nuclear condensation, cell shrinkage, membrane blebbing, and DNA fragmentation, plays an important role in many physiological and diseased conditions.Monitoring the cell's progression to apoptosis, detecting the apoptotic cells, and developing drugs that regulate the apoptotic pathways are the essential parts of basic research. Additionally, many diseases like cancer, autoimmune diseases and neurodegenerative diseases, like Alzheimer's Huntington's, and ALS involve either a failure of apoptosis to eliminate harmful cells or the inappropriate activation of apoptosis leading to loss of essential cells. The complexity of apoptosis regulation and the large numbers of molecular players in the apoptotic signaling pathways provide ample opportunity for developing therapeutics to modulate the pathway. Apoptosis can in general be divided into membrane mediate, cytoplasm mediated, mitochondria mediated, nucleus mediated and non-caspase mediated apoptosis. BioVision has developed various assays and products that can detect apoptosis at the early, middle, and late stages in apoptotic cascade.

The translocation of Phosphatidylserine (PS) which is normally confined in the inner membrane leaflet of viable cells, to the outer leaflet marks one of the earliest stages of apoptosis and leads to membrane mediated apoptosis. This PS translocation serves as a signal for attack by the phagocytic cells and their further clearance. Annexin V has a very high affinity for the exposed PS and this property has been utilized to make BioVision's Annexin V related apoptosis products. Our Annexin V conjugates are specially engineered to produce enhanced fluorescence signals and photostability, which perform considerably better than other similar products in the market. The Annexin V apoptosis kits are available in flexible sizes and are designed to sensitively and rapidly detect the membrane mediated apoptosis.
75b852b654485e51d332e6a05c7552f6.jpg


订阅商品讯息订阅商品讯息 Copyright © 2016 GenLabBiotech Co.,Ltd. All rights reserved.
Powered by www.url.com.tw